Efficient Monte Carlo methods for cyclic peptides

نویسندگان
چکیده

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Efficient Monte Carlo Methods for Cyclic Peptides

We present a new, biased Monte Carlo scheme for simulating complex, cyclic peptides. Backbone atoms are equilibrated with a biased rebridging scheme, and side-chain atoms are equilibrated with a look-ahead configurational bias Monte Carlo. Parallel tempering is shown to be an important ingredient in the construction of an efficient approach. Submitted to Molecular Physics.

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ژورنال

عنوان ژورنال: Molecular Physics

سال: 1999

ISSN: 0026-8976,1362-3028

DOI: 10.1080/00268979909482855